GOLGA5
Sign in to saveAlso known as GOLIM5, RFG5, ret-II, golgin A5, GOLGIN 84
Golgin subfamily A member 5 is a protein that in humans is encoded by the GOLGA5 gene.
Gene data
GOLGA5- Name
- golgin A5
- Type
- protein-coding
- Position
- 92,794,203–92,841,366 (+)
- Aliases
- GOLIM5, RFG5, ret-II
- Ensembl
- ENSG00000066455
- RefSeq RNA
- NM_005113.4, XM_011537420.4, XM_047432021.1, XM_054377146.1, XM_054377147.1
- RefSeq protein
- NP_005104.4, XP_011535722.1, XP_047287977.1, XP_054233121.1, XP_054233122.1
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. A pseudogene of this gene is located on the short arm of chromosome 5. [provided by RefSeq, Jul 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
golgin A5
- Symbol
- GOLGA5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:92,794,203-92,841,366
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 38009
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9950
- genomic end
- 92839947
- genomic start
- 92794305
- chromosome
- human chromosome 14
- cytogenetic location
- 14q32.12
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Golgin subfamily A member 5 is a protein that in humans is encoded by the GOLGA5 gene.
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins, whose members localize to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5.
Excerpted from Wikipedia’s “GOLGA5” article, available under the CC BY-SA 4.0 licence.