GORAB
Sign in to saveAlso known as GO, NTKLBP1, SCYL1BP1, golgin, RAB6 interacting
RAB6-interacting golgin also known as N-terminal kinase-like-binding protein 1 (NTKL-BP1) or SCY1-like 1-binding protein 1 (SCYL1-BP1) is a protein that in humans is encoded by the GORAB gene.
Gene data
GORAB- Name
- golgin, RAB6 interacting
- Type
- protein-coding
- Position
- 170,531,819–170,553,834 (+)
- Aliases
- GO, NTKLBP1, SCYL1BP1
- Ensembl
- ENSG00000120370
- RefSeq RNA
- NM_001146039.2, NM_001320252.2, NM_001410894.1, NM_152281.3, NR_027397.2
- RefSeq protein
- NP_001139511.2, NP_001307181.1, NP_001397823.1, NP_689494.3
This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
golgin, RAB6 interacting
- Symbol
- GORAB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:170,531,819-170,553,834
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 45113
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/92344
- genomic end
- 170553834
- genomic start
- 170531819
- chromosome
- human chromosome 1
- cytogenetic location
- 1q24.2
- genetic association
- gerodermia osteodysplastica
- expressed in
- gonad
via Wikidata · CC0
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Clinical significance
- See also
- References
- Further reading
- External links
RAB6-interacting golgin also known as N-terminal kinase-like-binding protein 1 (NTKL-BP1) or SCY1-like 1-binding protein 1 (SCYL1-BP1) is a protein that in humans is encoded by the GORAB gene.
== Function ==
Excerpted from Wikipedia’s “GORAB” article, available under the CC BY-SA 4.0 licence.