GRHPR
Sign in to saveAlso known as GLXR, GLYD, PH2, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate and hydroxypyruvate reductase
Glyoxylate reductase/hydroxypyruvate reductase is an enzyme that in humans is encoded by the GRHPR gene.
Gene data
GRHPR- Name
- glyoxylate and hydroxypyruvate reductase
- Type
- protein-coding
- Position
- 37,422,660–37,463,037 (+)
- Aliases
- GLXR, GLYD, PH2
- Ensembl
- ENSG00000137106
- RefSeq RNA
- NM_012203.2, XM_005251631.2, XM_017015320.3, XM_017015321.3, XM_017015323.3
- RefSeq protein
- NP_036335.1, XP_005251688.1, XP_016870809.1, XP_016870810.1, XP_016870812.1
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
glyoxylate and hydroxypyruvate reductase
- Symbol
- GRHPR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:37,422,660-37,463,037
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GRHPR PDB 2gcg.png
Show 8 more facts
- HomoloGene ID
- 49088
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9380
- genomic start
- 37422663
- chromosome
- human chromosome 9
- genomic end
- 37436987
- cytogenetic location
- 9p13.2
- Commons category
- GRHPR
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Glyoxylate reductase/hydroxypyruvate reductase is an enzyme that in humans is encoded by the GRHPR gene.
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. GRHPR mutation analysis needs to pay attention to primer design, because allele dropout can cause false-positive result.
Excerpted from Wikipedia’s “GRHPR” article, available under the CC BY-SA 4.0 licence.