GRXCR1
Sign in to saveAlso known as DFNB25, PPP1R88, glutaredoxin and cysteine rich domain containing 1
Glutaredoxin domain-containing cysteine-rich protein 1 is a protein that in humans is encoded by the GRXCR1 gene.
Gene data
GRXCR1- Name
- glutaredoxin and cysteine rich domain containing 1
- Type
- protein-coding
- Position
- 42,892,713–43,030,658 (+)
- Aliases
- DFNB25, PPP1R88
- Ensembl
- ENSG00000215203
- RefSeq RNA
- NM_001080476.3
- RefSeq protein
- NP_001073945.1
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
glutaredoxin and cysteine rich domain containing 1
- Symbol
- GRXCR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:42,892,713-43,030,658
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 42423
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/389207
- genomic end
- 43032675
- genomic start
- 42892713
- chromosome
- human chromosome 4
- cytogenetic location
- 4p13
- genetic association
- nonsyndromic deafness
- expressed in
- prostate
via Wikidata · CC0
~3 min read
Encyclopedic overview
2 sectionsContents
- Model organisms
- References
Glutaredoxin domain-containing cysteine-rich protein 1 is a protein that in humans is encoded by the GRXCR1 gene.
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells.
Excerpted from Wikipedia’s “GRXCR1” article, available under the CC BY-SA 4.0 licence.