GZMA

Name

granzyme A

Type

protein-coding

Position

55,102,641–55,110,252 (+)

Aliases

CTLA3, HFSP

Ensembl

ENSG00000145649

RefSeq RNA

NM_006144.4

RefSeq protein

NP_006135.2

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

granzyme A

Symbol

GZMA

Biotype

Protein coding

Organism

Homo sapiens

Location

5:55,102,641-55,110,252

Strand

Forward (+)

Assembly

GRCh38