H1-6
Sign in to saveAlso known as H1FT, H1t, dJ221C16.2, H1.6, histone cluster 1, H1t, histone cluster 1 H1 family member t, HIST1H1T, H1.6 linker histone, cluster member
Histone H1t is a protein that in humans is encoded by the HIST1H1T gene.
Gene data
H1-6- Name
- H1.6 linker histone, cluster member
- Type
- protein-coding
- Position
- 26,107,412–26,108,135 (−)
- Aliases
- H1.6, H1FT, H1t, HIST1H1T, dJ221C16.2
- Ensembl
- ENSG00000187475
- RefSeq RNA
- NM_005323.4
- RefSeq protein
- NP_005314.2
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
H1.6 linker histone, cluster member
- Symbol
- H1-6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:26,107,412-26,108,135
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 3889
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3010
- genomic end
- 26108135
- genomic start
- 26107412
- chromosome
- human chromosome 6
- cytogenetic location
- 6p22.2
- expressed in
- human musculoskeletal system
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Histone H1t is a protein that in humans is encoded by the HIST1H1T gene.
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Excerpted from Wikipedia’s “H1-6” article, available under the CC BY-SA 4.0 licence.