H2BC11
Sign in to saveAlso known as H2B/r, H2BFR, H2BJ, histone cluster 1, H2bj, histone cluster 1 H2B family member j, H2B clustered histone 11, HIST1H2BJ
Histone H2B type 1-J is a protein that in humans is encoded by the HIST1H2BJ gene.
Gene data
H2BC11- Name
- H2B clustered histone 11
- Type
- protein-coding
- Aliases
- H2B/r, H2BFR, H2BJ, HIST1H2BJ
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015].
via MyGene.info
Wikidata facts
- Image
- Cryo-EM structure of the human nucleosome Histone H2B type 1-J (2) 8KB5.png
Show 5 more facts
- HomoloGene ID
- 128594
- exact match
- identifiers.org/ncbigene/8970
- genomic start
- 27093676
- genomic end
- 27132795
- cytogenetic location
- 6p22.1
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Histone H2B type 1-J is a protein that in humans is encoded by the HIST1H2BJ gene.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.