H2BU1

Also known as H2Bb, histone cluster 3, H2bb, histone cluster 3 H2B family member b, H2B.U histone 1, HIST3H2BB

Histone H2B type 3-B is a protein that in humans is encoded by the HIST3H2BB gene.

Gene data

H2BC26

Name: H2B clustered histone 26
Type: protein-coding
Position: 228,458,103–228,463,104 (+)
Aliases: H2BU1, H2Bb, HIST3H2BB
Ensembl: ENSG00000285449
RefSeq RNA: NM_175055.3
RefSeq protein: NP_778225.1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015].

Gene Ontology

Biological process

innate immune response in mucosa chromatin organization antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide

Molecular function

DNA binding DNA binding structural constituent of chromatin structural constituent of chromatin protein heterodimerization activity

Cellular component

nucleosome nucleosome extracellular region nucleus nucleus nucleus nucleus nucleoplasm

Pathways

Neutrophil extracellular trap formation - Homo sapiens (human)Alcoholism - Homo sapiens (human)Viral carcinogenesis - Homo sapiens (human)Systemic lupus erythematosus - Homo sapiens (human)Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine

via MyGene.info

Gene · Ensembl

H2B clustered histone 26

Symbol: H2BC26
Biotype: Protein coding
Organism: Homo sapiens
Location: Chr HG2002_PATCH:49,306-51,669
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

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Encyclopedic overview

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Contents

References
Further reading

Histone H2B type 3-B is a protein that in humans is encoded by the HIST3H2BB gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 base pairs (bp) of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.

Excerpted from Wikipedia’s “H2BU1” article, available under the CC BY-SA 4.0 licence.

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