HOOK1

Name

hook microtubule tethering protein 1

Type

protein-coding

Position

59,814,786–59,876,370 (+)

Aliases

HK1

Ensembl

ENSG00000134709

RefSeq RNA

NM_015888.6, XM_006710676.2, XM_017001424.2, XM_024447520.2, XM_047422225.1

RefSeq protein

NP_056972.1, XP_006710739.1, XP_016856913.1, XP_024303288.1, XP_047278181.1

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

hook microtubule tethering protein 1

Symbol

HOOK1

Biotype

Protein coding

Organism

Homo sapiens

Location

1:59,814,786-59,876,370

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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