Structure via PubChem · Public domain (PubChem)
horsfiline
Sign in to saveAlso known as (-)-horsfiline
Horsfiline is an oxindole alkaloid found in the plant Horsfieldia superba, which is used in traditional herbal medicine. It has analgesic effects and has been the subject of research both to produce it synthetically by convenient routes and to develop analogues and derivatives which may have improved analgesic effects.
Chemical data
- Formula
- C13H16N2O2
- Molecular weight
- 232.28 g/mol
- IUPAC name
- (3R)-5-methoxy-1'-methylspiro[1H-indole-3,3'-pyrrolidine]-2-one
- SMILES
- CN1CC[C@]2(C1)C3=C(C=CC(=C3)OC)NC2=O
- InChIKey
- RVOLLKGLJIUGLG-ZDUSSCGKSA-N
- XLogP
- 0.8
- Polar surface area
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 232.121178
Show 4 more facts
- chemical formula
- C₁₃H₁₆N₂O₂
- isomeric SMILES
- CN1CC[C@]2(C1)C3=C(C=CC(=C3)OC)NC2=O
- canonical SMILES
- CN1CCC2(C1)C3=C(C=CC(=C3)OC)NC2=O
- found in taxon
- Horsfieldia superba
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Horsfiline is an oxindole alkaloid found in the plant Horsfieldia superba, which is used in traditional herbal medicine. It has analgesic effects and has been the subject of research both to produce it synthetically by convenient routes and to develop analogues and derivatives which may have improved analgesic effects.
It is a member of the spiroindolone class. Elacomine has a similar chemical structure.
Excerpted from Wikipedia’s “horsfiline” article, available under the CC BY-SA 4.0 licence.