IFRD1
Sign in to saveAlso known as PC4, TIS7, interferon related developmental regulator 1
Interferon-related developmental regulator 1 is a protein that in humans is encoded by the IFRD1 gene. The gene is expressed mostly in neutrophils, skeletal and cardiac muscle, the brain, and the pancreas. The rat and the mouse homolog genes of interferon-related developmental regulator 1 gene (and their proteins) are also known with the name PC4 and Tis21, respectively. IFRD1 is member of a gene family that comprises a second gene, IFRD2, also known as SKmc15.
Gene data
IFRD1- Name
- interferon related developmental regulator 1
- Type
- protein-coding
- Aliases
- PC4, TIS7
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010].
via MyGene.info
Gene · Ensembl
interferon related developmental regulator 1
- Symbol
- IFRD1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:112,422,887-112,481,017
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~3 min read
Encyclopedic overview
5 sectionsContents
- Clinical significance
- Inducer of muscle regeneration
- Interactions
- References
- Further reading
Interferon-related developmental regulator 1 is a protein that in humans is encoded by the IFRD1 gene. The gene is expressed mostly in neutrophils, skeletal and cardiac muscle, the brain, and the pancreas. The rat and the mouse homolog genes of interferon-related developmental regulator 1 gene (and their proteins) are also known with the name PC4 and Tis21, respectively. IFRD1 is member of a gene family that comprises a second gene, IFRD2, also known as SKmc15.
== Clinical significance ==
Excerpted from Wikipedia’s “IFRD1” article, available under the CC BY-SA 4.0 licence.