Structure via PubChem · Public domain (PubChem)
ilomastat
Sign in to saveAlso known as GM6001
Ilomastat (INN; development code GM6001; proprietary name Galardin) is a broad-spectrum matrix metalloproteinase inhibitor.
Chemical data
- Formula
- C20H28N4O4
- Molecular weight
- 388.5 g/mol
- IUPAC name
- (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide
- SMILES
- CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC
- InChIKey
- NITYDPDXAAFEIT-DYVFJYSZSA-N
- XLogP
- 0.9
- Polar surface area
- 123 Ų
- H-bond donors
- 5
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 388.211055376
Show 4 more facts
- chemical formula
- C₂₀H₂₈N₄O₄
- isomeric SMILES
- CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC
- Commons category
- Ilomastat
- canonical SMILES
- CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(=O)NO)CC(C)C
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Chembox | Name = GM6001 | ImageFile = Ilomastat.svg | ImageClass = skin-invert-image | ImageSize = | PIN = (3R)-N1-Hydroxy-N4-{(1S)-1-[(1H-indol-3-yl)methyl]-2-(methylamino)-2-oxoethyl}-3-(2-methylpropyl)butanediamide | OtherNames = Galardin, GM6001
| Section1 =
Excerpted from Wikipedia’s “ilomastat” article, available under the CC BY-SA 4.0 licence.