Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisItalianoNederlandsPortuguêsSvenskaالعربية
GeneQ18027942· pop 5· linked from 2 articles

INPP5A

Sign in to save

Also known as 5PTASE, inositol polyphosphate-5-phosphatase A

Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene.

Gene data

INPP5A
Name
inositol polyphosphate-5-phosphatase A
Type
protein-coding
Position
132,537,766–132,783,480 (+)
Aliases
5PTASE
Ensembl
ENSG00000068383
RefSeq RNA
NM_001321042.2, NM_005539.5, XM_017016204.2, XM_017016205.2, XM_054365796.1
RefSeq protein
NP_001307971.1, NP_005530.3, XP_016871693.1, XP_016871694.1, XP_054221771.1

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Inositol phosphate metabolism - Homo sapiens (human)Phosphatidylinositol signaling system - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)MetabolismInositol phosphate metabolismSynthesis of IP2, IP, and Ins in the cytosol

via MyGene.info

Gene · Ensembl

inositol polyphosphate-5-phosphatase A

Symbol
INPP5A
Biotype
Protein coding
Organism
Homo sapiens
Location
10:132,537,766-132,783,480
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
4045
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/3632
genomic end
134596979
genomic start
132537787
chromosome
human chromosome 10
cytogenetic location
10q26.3
expressed in
gastric mucosa
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene.

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins (1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Excerpted from Wikipedia’s “INPP5A” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0