INSM1
Sign in to saveAlso known as IA-1, IA1, INSM transcriptional repressor 1
Insulinoma-associated protein 1 is a protein that in humans is encoded by the INSM1 gene.
Gene data
INSM1- Name
- INSM transcriptional repressor 1
- Type
- protein-coding
- Position
- 20,368,104–20,370,949 (+)
- Aliases
- IA-1, IA1
- Ensembl
- ENSG00000173404
- RefSeq RNA
- NM_002196.3
- RefSeq protein
- NP_002187.1
Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
negative regulation of transcription by RNA polymerase IInegative regulation of transcription by RNA polymerase IInegative regulation of protein phosphorylationtype B pancreatic cell differentiationtype B pancreatic cell differentiationpancreatic A cell differentiationpancreatic A cell differentiationnoradrenergic neuron development
Molecular function
RNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription repressor activity, RNA polymerase II-specificDNA-binding transcription repressor activity, RNA polymerase II-specificDNA-binding transcription factor activityDNA-binding transcription factor activitycyclin bindingchromatin DNA binding
Pathways
via MyGene.info
Gene · Ensembl
INSM transcriptional repressor 1
- Symbol
- INSM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:20,368,104-20,370,949
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 31080
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3642
- genomic start
- 20368104
- genomic end
- 20351590
- chromosome
- human chromosome 20
- cytogenetic location
- 20p11.23
- expressed in
- putamen
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Insulinoma-associated protein 1 is a protein that in humans is encoded by the INSM1 gene.
== Function ==
Excerpted from Wikipedia’s “INSM1” article, available under the CC BY-SA 4.0 licence.