INTS1
Sign in to saveAlso known as INT1, NET28, integrator complex subunit 1, NDCAGF
gen de la especie Homo sapiens
Gene data
INTS1- Name
- integrator complex subunit 1
- Type
- protein-coding
- Position
- 1,469,895–1,504,418 (−)
- Aliases
- INT1, NDCAGF, NET28
- Ensembl
- ENSG00000164880
- RefSeq RNA
- NM_001080453.3, XM_011515260.2, XM_011515262.3, XM_054357857.1
- RefSeq protein
- NP_001073922.2, XP_011513562.1, XP_011513564.1, XP_054213832.1
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
snRNA processingsnRNA processingregulation of transcription elongation by RNA polymerase IIregulation of transcription elongation by RNA polymerase IIsnRNA 3'-end processingU2 snRNA 3'-end processingRNA polymerase II transcription initiation surveillanceRNA polymerase II transcription initiation surveillance
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
integrator complex subunit 1
- Symbol
- INTS1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:1,469,895-1,504,418
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 53111
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26173
- genomic end
- 1504389
- genomic start
- 1509913
- chromosome
- human chromosome 7
- cytogenetic location
- 7p22.3
Sources (4)
via Wikidata · CC0