IPO8

Name

importin 8

Type

protein-coding

Position

30,628,981–30,695,908 (−)

Aliases

RANBP8, VISS

Ensembl

ENSG00000133704

RefSeq RNA

NM_001190995.2, NM_006390.4, XM_017018691.3, XM_017018692.2, XM_017018693.3

RefSeq protein

NP_001177924.1, NP_006381.2, XP_016874180.1, XP_016874181.1, XP_016874182.1

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

via MyGene.info

Gene · Ensembl

importin 8

Symbol

IPO8

Biotype

Protein coding

Organism

Homo sapiens

Location

12:30,628,981-30,695,908

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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