- Date
- Date 1494–1498 ; 1499–1501 ; 1502–1504 ; 1508–1516 ; 1521–1526 ; 1526–1530 ; 1536–1538 ; 1542–1546 ; 1551–1559
- Location
- Primarily Italian Peninsula , also County of Flanders , the Rhineland , France , Spain and the Mediterranean Sea
- Result
- Peace of Cateau-Cambrésis Spanish–Imperial victory French defeat in Italy, with territorial gains in other theatres Mixed results among the Italian states English defeat
- Territorial changes
- Habsburg Spain sovereign over the kingdoms of Sicily , Naples (including the Presidi ), Sardinia and the Duchy of Milan Lorraine cedes Three Bishoprics to France France gains Calais from England Independent Savoyard state re-established Florence annexes Siena