Iteron
Sign in to saveIterons are directly repeated DNA sequences which play an important role in regulation of plasmid copy number in bacterial cells. It is one among the three negative regulatory elements found in plasmids which control its copy number. The others are antisense RNAs and ctRNAs. Iterons complex with cognate replication (Rep) initiator proteins to achieve the required regulatory effect.
~4 min read
Encyclopedic overview
5 sectionsContents
- Regulation of replication
- Limiting factors of initiation
- Replicon structure
- Replication initiator proteins
- References
Iterons are directly repeated DNA sequences which play an important role in regulation of plasmid copy number in bacterial cells. It is one among the three negative regulatory elements found in plasmids which control its copy number. The others are antisense RNAs and ctRNAs. Iterons complex with cognate replication (Rep) initiator proteins to achieve the required regulatory effect.
==Regulation of replication==
Excerpted from Wikipedia’s “Iteron” article, available under the CC BY-SA 4.0 licence.