🌐EnglishEnglishEspañolFrançaisItalianoNederlandsहिन्दीEntityQ11160442· pop 6· linked from 476 articlesK. P. RamanunniMalayalam-language Indian writerRecent publications · Crossref5 total works indexedBruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765 · 2011 · cited 678xTetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals · 2012 · cited 131xLenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase–dependent pathway · 2010 · cited 101xLenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells · 2008 · cited 95xIL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro · 2008 · cited 81xvia Crossref · CC0Wikidata factsAvailable in 5 languagesMalayalamPunjabiTamilTeluguvia Wikidata sitelinks · CC0ConnectionsJohann Ernst HanxledenEntityG. Sankara KurupEntityCategories1955 births20th-century Indian male writers20th-century Indian novelists20th-century Indian short story writers21st-century Indian novelistsBLP articles lacking sources from September 2022Indian male novelistsIndian male screenwritersIndian male short story writersLiving peopleMalayalam-language novelistsMalayalam screenwriters