KDSR
Sign in to saveAlso known as 6330410P18Rik, 9430079B08Rik, Fvt1, DHSR, SDR35C1, 3-ketodihydrosphingosine reductase, 3-dehydrosphinganine reductase
protein-coding gene in the species Homo sapiens
Gene data
KDSR- Name
- 3-ketodihydrosphingosine reductase
- Type
- protein-coding
- Aliases
- DHSR, EKVP4, FVT1, SDR35C1
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
3-ketodihydrosphingosine reductase
- Symbol
- KDSR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:63,327,566-63,367,615
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/2531
- HomoloGene ID
- 1539
- genomic start
- 63327726
- genomic end
- 63367228
- cytogenetic location
- 18q21.33
Sources (3)
via Wikidata · CC0