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Komagataella

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Komagataella is a methylotrophic yeast within the order Pichiales. It was found in the 1960s as Pichia pastoris, with its feature of using methanol as a source of carbon and energy. In 1995, P. pastoris was reassigned into the sole representative of genus Komagataella, becoming Komagataella pastoris. In 2005, it was found that almost all strains used industrially and in labs are a separate species, K. phaffii. Later studies have further distinguished new species in this genus, resulting in a total of 7 recognized species. It is not uncommon to see the old name still in use in the context of pr

In the Vinony graph

Vinony's link graph records 48 inbound references to Komagataella, and connects out to Global Biodiversity Information Facility, transformation and protein expression (biotechnology).

It is catalogued under topics including Ascomycota genera, Fungal models and Pichiomycetes.

Vinony links it to 7 Wikipedia language editions.

Species

GENUS

  1. KingdomFungi
  2. PhylumAscomycota
  3. ClassSaccharomycetes
  4. OrderSaccharomycetales
  5. FamilySaccharomycetaceae

via GBIF

Wikidata facts

Instance of
taxon
Parent taxon
Pichiaceae
Image
Pichia pastoris GS115 (Yang 2017).jpg
Show 5 more facts
taxon name
Komagataella
taxon rank
genus
taxonomic type
Komagataella pastoris
Commons category
Komagataella
taxon author citation
Y. Yamada, M. Matsuda, K. Maeda & Mikata
Sources (2)

via Wikidata · CC0

~13 min read

Encyclopedic overview

15 sections
Contents
  • Taxonomy
  • ''Komagataella'' in nature
  • Natural habitat
  • Reproduction
  • ''Komagataella'' as a model organism
  • ''Komagataella'' as a genetic model organism
  • ''Komagataella'' as an experimental model organism
  • ''Komagataella'' as expression system platform
  • Advantage
  • Disadvantage
  • Comparison with other expression systems
  • Industrial applications
  • Biotherapeutic production
  • Enzyme production
  • References

Komagataella is a methylotrophic yeast within the order Pichiales. It was found in the 1960s as Pichia pastoris, with its feature of using methanol as a source of carbon and energy. In 1995, P. pastoris was reassigned into the sole representative of genus Komagataella, becoming Komagataella pastoris. In 2005, it was found that almost all strains used industrially and in labs are a separate species, K. phaffii. Later studies have further distinguished new species in this genus, resulting in a total of 7 recognized species. It is not uncommon to see the old name still in use in the context of protein production, as of 2023; in less formal use, the yeast may confusingly be referred to as pichia.

After years of study, Komagataella is widely used in biochemical research and biotech industries. With strong potential for being an expression system for protein production, as well as being a model organism for genetic study, Komagataella phaffii has become important for biological research and biotech applications.

Excerpted from Wikipedia’s “Komagataella” article, available under the CC BY-SA 4.0 licence.

Available in 7 languages

via Wikidata sitelinks · CC0

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