Laurdan
Sign in to saveLaurdan is an organic compound which is used as a fluorescent dye when applied to fluorescence microscopy. It is used to investigate membrane qualities of the phospholipid bilayers of cell membranes. One of its most important characteristics is its sensitivity to membrane phase transitions as well as other alterations to membrane fluidity such as the penetration of water.
Research
837 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 353.27186474
Show 4 more facts
- canonical SMILES
- CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C
- subject has role
- fluorophore
- chemical formula
- C₂₄H₃₅NO
- Commons category
- Laurdan
via Wikidata · CC0
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Encyclopedic overview
6 sectionsContents
- History
- Chemical and physical properties
- Applications of Laurdan
- See also
- References
- External links
Laurdan is an organic compound which is used as a fluorescent dye when applied to fluorescence microscopy. It is used to investigate membrane qualities of the phospholipid bilayers of cell membranes. One of its most important characteristics is its sensitivity to membrane phase transitions as well as other alterations to membrane fluidity such as the penetration of water.
==History== Laurdan was first synthesized in 1979 by the Argentinian scientist Gregorio Weber, who started biomolecular fluorescence spectroscopy. His thesis, "Fluorescence of Riboflavin, Diasphorase and Related Substances", was the starting point for the application of fluorescence spectroscopy to biomolecules.
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