LCTL
Sign in to saveAlso known as KLG, KLPH, lactase like
Lactase-like is a protein that in humans is encoded by the LCTL gene. Lactase-like is a glycosidase enzyme.
Gene data
LCTL- Name
- lactase like
- Type
- protein-coding
- Aliases
- KLG, KLPH
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].
via MyGene.info
Gene · Ensembl
lactase like
- Symbol
- LCTL
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:66,547,179-66,566,003
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 70710
- exact match
- identifiers.org/ncbigene/197021
- genomic start
- 66839517
- genomic end
- 66565998
- cytogenetic location
- 15q22.31
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Lactase-like is a protein that in humans is encoded by the LCTL gene. Lactase-like is a glycosidase enzyme.
== Function == This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]