LGALS3BP
Sign in to saveAlso known as 90K, BTBD17B, CyCAP, M2BP, MAC-2-BP, TANGO10B, gp90, galectin 3 binding protein
Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene.
Gene data
LGALS3BP- Name
- galectin 3 binding protein
- Type
- protein-coding
- Position
- 78,970,308–78,979,969 (−)
- Aliases
- 90K, BTBD17B, CyCAP, M2BP, MAC-2-BP, TANGO10B, gp90
- Ensembl
- ENSG00000108679
- RefSeq RNA
- NM_005567.4, XM_054316043.1
- RefSeq protein
- NP_005558.1, XP_054172018.1
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
galectin 3 binding protein
- Symbol
- LGALS3BP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:78,970,308-78,979,969
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- Further reading
Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene.
== Function ==
Excerpted from Wikipedia’s “LGALS3BP” article, available under the CC BY-SA 4.0 licence.