LGALS9

Also known as HUAT, LGALS9A, galectin 9

Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9 gene.

Gene data

LGALS9

Name: galectin 9
Type: protein-coding
Aliases: HUAT, LGALS9A

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

galectin 9

Symbol: LGALS9
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:27,629,798-27,649,561
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein LGALS9 PDB 2EAK.png

Show 8 more facts

HomoloGene ID: 32078
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/3965
genomic end: 25976586
genomic start: 25956824
chromosome: human chromosome 17
cytogenetic location: 17q11.2
expressed in: appendix

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

5 sections

Contents

Function
Clinical significance
References
Further reading
External links

Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9 gene.

== Function ==

Excerpted from Wikipedia’s “LGALS9” article, available under the CC BY-SA 4.0 licence.