LIMA1
Sign in to saveAlso known as EPLIN, SREBP3, LIM domain and actin binding 1, LDLCQ8
LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.
Gene data
LIMA1- Name
- LIM domain and actin binding 1
- Type
- protein-coding
- Position
- 50,175,788–50,283,550 (−)
- Aliases
- EPLIN, LDLCQ8, SREBP3
- Ensembl
- ENSG00000050405
- RefSeq RNA
- NM_001113546.2, NM_001113547.2, NM_001243775.2, NM_001394886.1, NM_001394887.1
- RefSeq protein
- NP_001107018.1, NP_001107019.1, NP_001230704.1, NP_001381815.1, NP_001381816.1
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
LIM domain and actin binding 1
- Symbol
- LIMA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:50,175,788-50,283,550
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.
EPLIN is a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles (Maul et al., 2003).[supplied by OMIM]
Excerpted from Wikipedia’s “LIMA1” article, available under the CC BY-SA 4.0 licence.