Lipstatin is a potent, irreversible inhibitor of pancreatic lipase. It is a natural product that was first isolated from the actinobacterium Streptomyces toxytricini.
Lipstatin is a potent, irreversible inhibitor of pancreatic lipase. It is a natural product that was first isolated from the actinobacterium Streptomyces toxytricini.
The popular antiobesity drug orlistat (trade names Xenical and alli) is a saturated derivative of lipstatin.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).