LPCAT1
Sign in to saveAlso known as lysophosphatidylcholine acyltransferase 1, AYTL2, PFAAP3, lpcat, AGPAT10, AGPAT9, LPCAT-1, lysoPAFAT
Lysophosphatidylcholine acyltransferase 1 is a protein in humans that is encoded by the LPCAT1 gene.
Gene data
LPCAT1- Name
- lysophosphatidylcholine acyltransferase 1
- Type
- protein-coding
- Aliases
- AGPAT10, AGPAT9, AYTL2, LPCAT-1, LPLAT8, PFAAP3, lpcat, lysoPAFAT
This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9871
- genomic start
- 1456595
- exact match
- identifiers.org/ncbigene/79888
- genomic end
- 1523962
- cytogenetic location
- 5p15.33
Sources (4)
via Wikidata · CC0
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Article
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- References
Lysophosphatidylcholine acyltransferase 1 is a protein in humans that is encoded by the LPCAT1 gene.
Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis.