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GeneQ18040547· pop 6· linked from 3 articles

LUC7L3

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Also known as CRA, CREAP-1, CROP, LUC7A, OA48-18, hLuc7A, LUC7 like 3 pre-mRNA splicing factor

LUC7 like 3 pre-mRNA splicing factor (LUC7L3), also known as Cisplatin resistance-associated overexpressed protein, or CROP, is a human gene.

Gene data

LUC7L3
Name
LUC7 like 3 pre-mRNA splicing factor
Type
protein-coding
Position
50,719,565–50,756,219 (+)
Aliases
CRA, CREAP-1, CROP, LUC7A, OA48-18, hLuc7A
Ensembl
ENSG00000108848
RefSeq RNA
NM_001330330.2, NM_006107.4, NM_016424.5, XM_005257449.3, XM_005257452.2
RefSeq protein
NP_001317259.1, NP_006098.2, NP_057508.2, XP_005257506.1, XP_005257509.1

This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009].

Gene Ontology

Pathways

mRNA Splicing - Major PathwaymRNA SplicingProcessing of Capped Intron-Containing Pre-mRNAMetabolism of RNA

via MyGene.info

Gene · Ensembl

LUC7 like 3 pre-mRNA splicing factor

Symbol
LUC7L3
Biotype
Protein coding
Organism
Homo sapiens
Location
17:50,719,565-50,756,219
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
75056
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/51747
genomic end
50756219
genomic start
50719565
chromosome
human chromosome 17
cytogenetic location
17q21.33
expressed in
corpus callosum
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • References
  • External links
  • Further reading

LUC7 like 3 pre-mRNA splicing factor (LUC7L3), also known as Cisplatin resistance-associated overexpressed protein, or CROP, is a human gene.

This gene encodes a cisplatin resistance-associated overexpressed protein (CROP). The N-terminal half of the CROP contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Excerpted from Wikipedia’s “LUC7L3” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0