MED13
Sign in to saveAlso known as ARC250, DRIP250, HSPC221, THRAP1, TRAP240, mediator complex subunit 13, MRD61
Mediator complex subunit 13 is a protein that in humans is encoded by the MED13 gene.
Gene data
MED13- Name
- mediator complex subunit 13
- Type
- protein-coding
- Position
- 61,942,546–62,065,365 (−)
- Aliases
- ARC250, DRIP250, HSPC221, MRD61, THRAP1, TRAP240
- Ensembl
- ENSG00000108510
- RefSeq RNA
- NM_005121.3, XM_011525551.3, XM_011525552.3, XM_011525553.4, XM_054318108.1
- RefSeq protein
- NP_005112.2, XP_011523853.1, XP_011523854.1, XP_011523855.1, XP_054174083.1
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mediator complex subunit 13
- Symbol
- MED13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:61,942,546-62,065,365
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Mediator complex subunit 13 is a protein that in humans is encoded by the MED13 gene.
== Function ==
Excerpted from Wikipedia’s “MED13” article, available under the CC BY-SA 4.0 licence.