MED13

Name

mediator complex subunit 13

Type

protein-coding

Position

61,942,546–62,065,365 (−)

Aliases

ARC250, DRIP250, HSPC221, MRD61, THRAP1, TRAP240

Ensembl

ENSG00000108510

RefSeq RNA

NM_005121.3, XM_011525551.3, XM_011525552.3, XM_011525553.4, XM_054318108.1

RefSeq protein

NP_005112.2, XP_011523853.1, XP_011523854.1, XP_011523855.1, XP_054174083.1

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mediator complex subunit 13

Symbol

MED13

Biotype

Protein coding

Organism

Homo sapiens

Location

17:61,942,546-62,065,365

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

The IDRc bound human core Mediator complex - Mediator of RNA polymerase II transcription subunit 13 (3) 8TRH.png

via Wikidata · CC0