metacetamol
Sign in to saveAlso known as 3-hydroxyacetanilide, m-acetamidophenol, N-acetyl-m-aminophenol, m-(acetylamino)phenol, m-hydroxyacetanilide, 3-acetamidophenol, 3-(acetylamino)phenol, 3-(acetylamino)-1-hydroxybenzene
Metacetamol (developmental code name BS-749), also known as 3-hydroxyacetanilide and AMAP, is a non-toxic regioisomer of paracetamol with analgesic and antipyretic properties, but has never been marketed as a drug.
Research
11 papers- Synthesis and Evaluation of Novel Metacetamol Derivatives with Hydrazone Moiety as Anticancer and Antimicrobial Agents.Chemistry & biodiversity · 2023
- A novel crystal form of metacetamol: the first example of a hydrated form.Acta crystallographica. Section C, Structural chemistry · 2019
- Quantitative analysis of paracetamol, metacetamol, and orthocetamol in equine urine from racehorses in Japan using liquid chromatography-electrospray ionization-tandem mass spectrometry.Drug testing and analysis · 2020
- The Pressure-Temperature Phase Diagram of Metacetamol and Its Comparison to the Phase Diagram of Paracetamol.Journal of pharmaceutical sciences · 2017
- A Novel Drug-Drug Cocrystal of Levofloxacin and Metacetamol: Reduced Hygroscopicity and Improved Photostability of Levofloxacin.Journal of pharmaceutical sciences · 2019
via PubMed
Wikidata facts
- Subclass of
- anilides
- Mass
- 151.063
Show 7 more facts
- World Health Organisation international non-proprietary name
- metacetamol
- canonical SMILES
- CC(=O)NC1=CC(=CC=C1)O
- subject has role
- analgesic
- chemical formula
- C₈H₉NO₂
- Commons category
- Metacetamol
- melting point
- 148
- found in taxon
- Nicotiana tabacum
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
1 sectionsContents
- References
Metacetamol (developmental code name BS-749), also known as 3-hydroxyacetanilide and AMAP, is a non-toxic regioisomer of paracetamol with analgesic and antipyretic properties, but has never been marketed as a drug.
Metacetamol is known to have several polymorphs. Form II is metastable, while form I is stable. Metacetamol polymorph II transforms to form I upon water moisture or direct contact with water and other popular solvents. Metacetamol II form may be obtained on cooling in narrow temperature regime.
Excerpted from Wikipedia’s “metacetamol” article, available under the CC BY-SA 4.0 licence.