Structure via PubChem · Public domain (PubChem)
methylparaben
Sign in to saveAlso known as nipagin, INS No. 218, INS number 218, E 218, Methyl parahydroxybenzoate, FEMA No. 2710, p-carbomethoxyphenol, p-methoxycarbonylphenol
thumb|right|UV-visible spectrum of methylparaben
Chemical data
- Formula
- C8H8O3
- Molecular weight
- 152.15 g/mol
- IUPAC name
- methyl 4-hydroxybenzoate
- SMILES
- COC(=O)C1=CC=C(C=C1)O
- InChIKey
- LXCFILQKKLGQFO-UHFFFAOYSA-N
- XLogP
- 2
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,307 papers- Methylparaben and propylparaben promote bladder cancer invasion via MMP2 and PPARG modulation.Ecotoxicology and environmental safety · 2025
- Unraveling the Mechanisms of Osteoporosis Triggered by Methylparaben and Monomethyl Phthalate through Integrated Mendelian Randomization, In Silico Simulations, and Experimental Validation.Environmental science & technology · 2026
- Methylparaben-induced regulation of estrogenic signaling in human neutrophils.Molecular and cellular endocrinology · 2021
- Methylparaben toxicity and its removal by microalgae Chlorella vulgaris and Phaeodactylum tricornutum.Journal of hazardous materials · 2023
- Methylparaben as a preservative in the development of a multi-dose HPV-2 vaccine.Human vaccines & immunotherapeutics · 2022
via PubMed
Wikidata facts
Show 7 more facts
- found in taxon
- Peperomia humilis
- chemical formula
- C₈H₈O₃
- canonical SMILES
- COC(=O)C1=CC=C(C=C1)O
- subject has role
- allergen
- MCN code
- 2918.29.22
- melting point
- 127
- Commons category
- Methylparaben
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Natural occurrences
- Uses
- Safety
- References
- External links
thumb|right|UV-visible spectrum of methylparaben
Methylparaben (methyl paraben) one of the parabens, is a preservative with the chemical formula . It is the methyl ester of p-hydroxybenzoic acid. Several related esters are known (ethyl-, propyl-, butylparaben). Together they are the most common preservatives in cosmetics and foods. Among their advantages, parabens are inexpensive, colorless, stable, odorless, and readily biodegraded.
Excerpted from Wikipedia’s “methylparaben” article, available under the CC BY-SA 4.0 licence.