MICAL1
Sign in to saveAlso known as MICAL, MICAL-1, NICAL, microtubule associated monooxygenase, calponin and LIM domain containing 1
NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene.
Gene data
MICAL1- Name
- microtubule associated monooxygenase, calponin and LIM domain containing 1
- Type
- protein-coding
- Position
- 109,444,062–109,465,968 (−)
- Aliases
- MICAL, MICAL-1, NICAL
- Ensembl
- ENSG00000135596
- RefSeq RNA
- NM_001159291.2, NM_001286613.2, NM_022765.4
- RefSeq protein
- NP_001152763.1, NP_001273542.1, NP_073602.3
This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
- Image
- Protein MICAL1 PDB 1wyl.png
Show 3 more facts
- HomoloGene ID
- 11246
- exact match
- identifiers.org/ncbigene/64780
- cytogenetic location
- 6q21
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene.
==Interactions== MICAL1 has been shown to interact with NEDD9 and RAB1A.