MIEF1
Sign in to saveAlso known as HSU79252, MID51, SMCR7L, dJ1104E15.3, mitochondrial elongation factor 1, AltMIEF1, MIEF1-MP
Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.
Gene data
MIEF1- Name
- mitochondrial elongation factor 1
- Type
- protein-coding
- Position
- 39,499,432–39,518,132 (+)
- Aliases
- D3A, HSU79252, MID51, OPA14, SMCR7L, dJ1104E15.3
- Ensembl
- ENSG00000100335
- RefSeq RNA
- NM_001304564.2, NM_001394030.1, NM_013298.1, NM_019008.6, NR_130789.2
- RefSeq protein
- NP_001291493.1, NP_061881.2
Enables ADP binding activity; GDP binding activity; and identical protein binding activity. Involved in several processes, including positive regulation of mitochondrial fission; positive regulation of mitochondrial translation; and positive regulation of protein targeting to membrane. Located in mitochondrial matrix and mitochondrial outer membrane. Colocalizes with mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mitochondrial elongation factor 1
- Symbol
- MIEF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:39,499,432-39,518,132
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.
==Function== The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.
Excerpted from Wikipedia’s “MIEF1” article, available under the CC BY-SA 4.0 licence.