MIEF1
Sign in to saveAlso known as HSU79252, MID51, SMCR7L, dJ1104E15.3, mitochondrial elongation factor 1, AltMIEF1, MIEF1-MP
Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.
Gene data
MIEF1- Name
- mitochondrial elongation factor 1
- Type
- protein-coding
- Aliases
- D3A, HSU79252, MID51, OPA14, SMCR7L, dJ1104E15.3
Enables ADP binding activity; GDP binding activity; and identical protein binding activity. Involved in several processes, including positive regulation of mitochondrial fission; positive regulation of mitochondrial translation; and positive regulation of protein targeting to membrane. Located in mitochondrial matrix and mitochondrial outer membrane. Colocalizes with mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
mitochondrial elongation factor 1
- Symbol
- MIEF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:39,499,432-39,518,132
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 10374
- exact match
- identifiers.org/ncbigene/54471
- cytogenetic location
- 22q13.1
- genomic start
- 39895437
- genomic end
- 39914137
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.
==Function== The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.