イノシトールオキシゲナーゼ

Also known as ALDRL6, myo-inositol oxygenase

protein-coding gene in the species Homo sapiens

Gene data

MIOX

Name: myo-inositol oxygenase
Type: protein-coding
Position: 50,486,784–50,490,648 (+)
Aliases: ALDRL6
Ensembl: ENSG00000100253
RefSeq RNA: NM_017584.6, XM_005261925.5, XM_011530705.3, XM_047441443.1, XM_054325787.1
RefSeq protein: NP_060054.4, XP_005261982.1, XP_011529007.1, XP_047297399.1, XP_054181762.1

Enables ferric iron binding activity and inositol oxygenase activity. Involved in inositol catabolic process. Predicted to be located in cytoplasm and inclusion body. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

inositol catabolic process inositol catabolic process inositol catabolic process inositol catabolic process

Molecular function

iron ion binding alcohol dehydrogenase (NADP+) activity alcohol dehydrogenase (NADP+) activity alcohol dehydrogenase (NADP+) activity ferric iron binding oxidoreductase activity, acting on NAD(P)H inositol oxygenase activity inositol oxygenase activity

Cellular component

cytoplasm cytoplasm cytosol inclusion body

Pathways

Ascorbate and aldarate metabolism - Homo sapiens (human)Inositol phosphate metabolism - Homo sapiens (human)Metabolism Inositol phosphate metabolism Synthesis of IP2, IP, and Ins in the cytosol

via MyGene.info

Wikidata facts

Instance of: gene
Image: Mouse miox.png

Show 4 more facts

HomoloGene ID: 9732
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/55586
cytogenetic location: 22q13.33

Sources (4)

via Wikidata · CC0

Article · 日本語

イノシトールオキシゲナーゼ（inositol oxygenase）は、リシン分解酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 myo-イノシトール + O2 D-グルクロン酸 + H2O 反応式の通り、この酵素の基質はmyo-イノシトールとO2、生成物はD-グルクロン酸とH2Oである。補因子としてFADを用いる。組織名はL-lysine:oxygen 2-oxidoreductase (decarboxylating)で、別名にlysine oxygenase、lysine monooxygenase、L-lysine-2-monooxygenaseがある。

Abstract from DBpedia / Wikipedia · CC BY-SA

Available in 8 languages

via Wikidata sitelinks · CC0