MYL12A
Sign in to saveAlso known as HEL-S-24, MLCB, MRCL3, MRLC3, MYL2B, MLC-2B, myosin light chain 12A
Myosin regulatory light chain 12A is a protein that in humans is encoded by the MYL12A gene.
Gene data
MYL12A- Name
- myosin light chain 12A
- Type
- protein-coding
- Position
- 3,247,481–3,256,730 (+)
- Aliases
- HEL-S-24, MLC-2B, MLCB, MRCL3, MRLC3, MYL2B
- Ensembl
- ENSG00000101608
- RefSeq RNA
- NM_001303047.2, NM_001303048.1, NM_001303049.2, NM_006471.4, XM_047437270.1
- RefSeq protein
- NP_001289976.1, NP_001289977.1, NP_001289978.1, NP_006462.1, XP_047293226.1
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
myosin light chain 12A
- Symbol
- MYL12A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:3,247,481-3,256,730
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Myosin regulatory light chain 12A is a protein that in humans is encoded by the MYL12A gene.
==See also== Myosin light chain
Excerpted from Wikipedia’s “MYL12A” article, available under the CC BY-SA 4.0 licence.