MYT1L

Name

myelin transcription factor 1 like

Type

protein-coding

Position

1,789,113–2,331,664 (−)

Aliases

MRD39, NZF1, ZC2H2C2, ZC2HC4B, myT1-L

Ensembl

ENSG00000186487

RefSeq RNA

NM_001303052.2, NM_001329844.2, NM_001329845.1, NM_001329846.3, NM_001329847.2

RefSeq protein

NP_001289981.1, NP_001316773.1, NP_001316774.1, NP_001316775.1, NP_001316776.1

This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Jul 2017].

via MyGene.info

Gene · Ensembl

myelin transcription factor 1 like

Symbol

MYT1L

Biotype

Protein coding

Organism

Homo sapiens

Location

2:1,789,113-2,331,664

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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