NAP1L4
Sign in to saveAlso known as NAP1L4b, NAP2, NAP2L, hNAP2, nucleosome assembly protein 1 like 4
Nucleosome assembly protein 1-like 4 is a protein that in humans is encoded by the NAP1L4 gene.
Gene data
NAP1L4- Name
- nucleosome assembly protein 1 like 4
- Type
- protein-coding
- Position
- 2,944,429–2,992,416 (−)
- Aliases
- NAP1L4b, NAP2, NAP2L, hNAP2
- Ensembl
- ENSG00000273562
- RefSeq RNA
- NM_001369375.1, NM_001369376.1, NM_001369377.1, NM_001369378.1, NM_001369379.1
- RefSeq protein
- NP_001356304.1, NP_001356305.1, NP_001356306.1, NP_001356307.1, NP_001356308.1
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Cellular component
via MyGene.info
Gene · Ensembl
nucleosome assembly protein 1 like 4
- Symbol
- NAP1L4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:2,944,429-2,992,416
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 133933
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4676
- chromosome
- human chromosome 11
- genomic start
- 2965667
- genomic end
- 3013607
- cytogenetic location
- 11p15.4
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Nucleosome assembly protein 1-like 4 is a protein that in humans is encoded by the NAP1L4 gene.
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.
Excerpted from Wikipedia’s “NAP1L4” article, available under the CC BY-SA 4.0 licence.