Nardosinone
Sign in to saveNardosinone is a sesquiterpene and chemical constituent of Nardostachys jatamansi. In in vitro studies, the compound has demonstrated concentration-dependent enhancement of bucladesine and staurosporine-induced neurite outgrowth. Nardosinone has similarly been demonstrated to enhance NGF-mediated neurite outgrowth and synaptogenesis from PC12D cells.
Wikidata facts
- Mass
- 250.156895
Show 3 more facts
- chemical formula
- C₁₅H₂₂O₃
- isomeric SMILES
- C[C@@H]1CCC=C2[C@]1([C@H]3[C@@H](CC2=O)OOC3(C)C)C
- canonical SMILES
- CC1CCC=C2C1(C3C(CC2=O)OOC3(C)C)C
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Nardosinone is a sesquiterpene and chemical constituent of Nardostachys jatamansi. In in vitro studies, the compound has demonstrated concentration-dependent enhancement of bucladesine and staurosporine-induced neurite outgrowth. Nardosinone has similarly been demonstrated to enhance NGF-mediated neurite outgrowth and synaptogenesis from PC12D cells.
Additionally, nardosinone has demonstrated cytotoxic activity against cultured P-388 lymphocytic leukemia cells.