neurogenesis
Sign in to saveAlso known as nervous system cell generation, GO:0022008
Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). This occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular zone astrocytes, and subgranular zone radial astrocytes, among others.
Key facts
- Embryology.Name
- Neurogenesis
- Embryology.Image
- Journal.pone.0001604.g001 small.jpg
- Embryology.Caption
- A neurosphere of neural stem cells in rat embryo spreads out into a single layer of cells. A) Neurosphere of subventricular zone cells after two days in culture. B) Shows the neurosphere at four days in culture and cells migrating away. C) Cells at the periphery of the neurosphere mostly having extending processes.
via Wikipedia infobox
Research
43,586 papers- Neurogenesis in aging and age-related neurodegenerative diseases.Ageing research reviews · 2022
- Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis.Journal of neuroinflammation · 2023
- An Overview of Adult Neurogenesis.Advances in experimental medicine and biology · 2021
- Adult hippocampal neurogenesis and its impairment in Alzheimer's disease.Zoological research · 2022
- Role of histone modifications in neurogenesis and neurodegenerative disease development.Ageing research reviews · 2024
via PubMed
~10 min read
Encyclopedic overview
12 sectionsContents
- In mammals
- Developmental neurogenesis
- Epigenetic modification
- Adult neurogenesis
- Subventricular zone
- Hippocampus
- In other organisms
- Substance-induced neurogenesis
- Other findings
- See also
- References
- External links
Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). This occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular zone astrocytes, and subgranular zone radial astrocytes, among others.
Neurogenesis is most active during embryonic development and is responsible for producing all the various types of neurons of the organism, but it continues throughout adult life in a variety of organisms. Once born, neurons do not divide (see mitosis), and many will live the lifespan of the animal, except under extraordinary and usually pathogenic circumstances.
Excerpted from Wikipedia’s “neurogenesis” article, available under the CC BY-SA 4.0 licence.