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nociceptor

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Also known as nociceptors, pain receptor cell, pain receptor, nocireceptor

A nociceptor () is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception.

~14 min read

Encyclopedic overview

17 sections
Contents
  • Terminology
  • Scientific investigation
  • Location
  • Types and functions
  • Thermal
  • Mechanical
  • Chemical
  • Sleeping/silent
  • Polymodal
  • Pathway
  • Ascending
  • Descending
  • Sensitivity
  • Neural development
  • In other animals
  • See also
  • References

A nociceptor () is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception.

==Terminology== Nociception and pain are usually evoked only by pressures and temperatures that are potentially damaging to tissues. This barrier or threshold contrasts with the more sensitive visual, auditory, olfactory, taste, and somatosensory responses to stimuli. The experience of pain is individualistic and can be suppressed by stress or exacerbated by anticipation. Simple activation of a nociceptor does not always lead to perceived pain, because the latter also depends on the frequency of the action potentials, integration of pre- and postsynaptic signals, and influences from higher or central processes.

Excerpted from Wikipedia’s “nociceptor” article, available under the CC BY-SA 4.0 licence.