NOL6
Sign in to saveAlso known as NRAP, UTP22, bA311H10.1, nucleolar protein 6
Nucleolar protein 6 is a protein that in humans is encoded by the NOL6 gene.
Gene data
NOL6- Name
- nucleolar protein 6
- Type
- protein-coding
- Position
- 33,461,353–33,473,930 (−)
- Aliases
- NRAP, UTP22, bA311H10.1
- Ensembl
- ENSG00000165271
- RefSeq RNA
- NM_022917.5, NM_130793.3, NM_139235.4, XM_047423740.1, XM_054363572.1
- RefSeq protein
- NP_075068.2, NP_631981.2, XP_047279696.1, XP_054219547.1
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
nucleolar protein 6
- Symbol
- NOL6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:33,461,353-33,473,930
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Nucleolar protein 6 is a protein that in humans is encoded by the NOL6 gene.
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
Excerpted from Wikipedia’s “NOL6” article, available under the CC BY-SA 4.0 licence.