NOP53
Sign in to saveAlso known as PICT-1, PICT1, GLTSCR2, glioma tumor suppressor candidate region gene 2, NOP53 ribosome biogenesis factor
Glioma tumor suppressor candidate region gene 2 protein is a protein that in humans is encoded by the GLTSCR2 gene.
Gene data
NOP53- Name
- NOP53 ribosome biogenesis factor
- Type
- protein-coding
- Position
- 47,745,481–47,758,208 (+)
- Aliases
- GLTSCR2, PICT-1, PICT1
- Ensembl
- ENSG00000105373
- RefSeq RNA
- NM_015710.5
- RefSeq protein
- NP_056525.2
Enables 5S rRNA binding activity; identical protein binding activity; and p53 binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; regulation of cellular protein metabolic process; and regulation of intracellular signal transduction. Located in cytosol; fibrillar center; and nucleoplasm. Colocalizes with rDNA heterochromatin. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
NOP53 ribosome biogenesis factor
- Symbol
- NOP53
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:47,745,481-47,758,208
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 44130
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/29997
- genomic end
- 48260315
- genomic start
- 47745546
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.33
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Glioma tumor suppressor candidate region gene 2 protein is a protein that in humans is encoded by the GLTSCR2 gene.
==References==
Excerpted from Wikipedia’s “NOP53” article, available under the CC BY-SA 4.0 licence.