norlevorphanol
Sign in to saveAlso known as (−)-3-hydroxymorphinan, (−)-morphinan-3-ol
Norlevorphanol is an opioid analgesic of the morphinan family that was never marketed. It is the levo-isomer of 3-hydroxymorphinan (morphinan-3-ol). Norlevorphanol is a Schedule I Narcotic controlled substance in the United States with an ACSCN of 9634 and in 2014 it had an annual aggregate manufacturing quota of 52 grams. It is used as the hydrobromide (free base conversion ratio 0.750) and hydrochloride (0.870). It has morphine-like pharmacological properties.
Research
34 papers- Identifying Levorphanol Ingestion Using Urine Biomarkers in Health Care Patients.Pain physician · 2018
- The metabolism of (-)-3-phenoxy-N-methylmorphinan in dogs.Drug metabolism and disposition: the biological fate of chemicals · 1981
- Neuropsychotoxicity of abused drugs: potential of dextromethorphan and novel neuroprotective analogs of dextromethorphan with improved safety profiles in terms of abuse and neuroprotective effects.Journal of pharmacological sciences · 2008
- 3-hydroxymorphinan enhances mitochondrial biogenesis and adipocyte browning through AMPK-dependent pathway.Biochemical and biophysical research communications · 2021
- Phenotypic differences in dextromethorphan metabolism.Pharmaceutical research · 1989
via PubMed
Wikidata facts
- Mass
- 243.162314292
Show 3 more facts
- chemical formula
- C₁₆H₂₁NO
- canonical SMILES
- OC1=CC=C2C(=C1)C34CCNC(C2)C4CCCC3
- isomeric SMILES
- Oc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)NCC3
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Article
2 sectionsContents
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Norlevorphanol is an opioid analgesic of the morphinan family that was never marketed. It is the levo-isomer of 3-hydroxymorphinan (morphinan-3-ol). Norlevorphanol is a Schedule I Narcotic controlled substance in the United States with an ACSCN of 9634 and in 2014 it had an annual aggregate manufacturing quota of 52 grams. It is used as the hydrobromide (free base conversion ratio 0.750) and hydrochloride (0.870). It has morphine-like pharmacological properties.
==See also== Levallorphan Levorphanol Levomethorphan