NPLOC4
Sign in to saveAlso known as NPL4, NPL4 homolog, ubiquitin recognition factor
Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene.
Gene data
NPLOC4- Name
- NPL4 homolog, ubiquitin recognition factor
- Type
- protein-coding
- Position
- 81,556,887–81,648,465 (−)
- Aliases
- NPL4
- Ensembl
- ENSG00000182446
- RefSeq RNA
- NM_001369698.1, NM_001437986.1, NM_001438810.1, NM_017921.4, NR_130139.1
- RefSeq protein
- NP_001356627.1, NP_001424915.1, NP_001425739.1, NP_060391.2, XP_011523282.1
Predicted to enable ATPase binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to K48-linked polyubiquitin modification-dependent protein binding activity and K63-linked polyubiquitin modification-dependent protein binding activity. Involved in negative regulation of RIG-I signaling pathway; negative regulation of type I interferon production; and proteolysis involved in cellular protein catabolic process. Located in nucleus. Part of UFD1-NPL4 complex and VCP-NPL4-UFD1 AAA ATPase complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
NPL4 homolog, ubiquitin recognition factor
- Symbol
- NPLOC4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,556,887-81,648,465
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene.
== Interactions ==
Excerpted from Wikipedia’s “NPLOC4” article, available under the CC BY-SA 4.0 licence.