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GeneQ18041252· pop 6· linked from 2 articles

NSMCE4A

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Also known as C10orf86, NS4EA, NSE4A, NSE4 homolog A, SMC5-SMC6 complex component

Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene.

Gene data

NSMCE4A

Name: NSE4A component of SMC5/6 complex
Type: protein-coding
Position: 121,953,334–121,975,300 (−)
Aliases: C10orf86, NS4EA, NSE4A
Ensembl: ENSG00000107672
RefSeq RNA: NM_001167865.2, NM_001411073.1, NM_017615.3, XM_005269929.5, XM_005269930.5
RefSeq protein: NP_001161337.1, NP_001398002.1, NP_060085.2, XP_005269986.1, XP_005269987.1

Involved in positive regulation of response to DNA damage stimulus. Located in nuclear body. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

double-strand break repair via homologous recombination DNA repair DNA repair DNA damage response protein sumoylation regulation of telomere maintenance chromatin looping

Molecular function

protein binding

Cellular component

chromosome, telomeric region chromosome, telomeric region nucleus nucleus nucleoplasm nucleoplasm chromosome Smc5-Smc6 complex

Pathways

SUMOylation SUMOylation of DNA damage response and repair proteins SUMO E3 ligases SUMOylate target proteins Metabolism of proteins Post-translational protein modification

via MyGene.info

Gene · Ensembl

NSE4A component of SMC5/6 complex

Symbol: NSMCE4A
Biotype: Protein coding
Organism: Homo sapiens
Location: 10:121,953,334-121,975,300
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene.

==References==

Excerpted from Wikipedia’s “NSMCE4A” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0