NUDT21

Also known as CFIM25, CPSF5, nudix hydrolase 21

Cleavage and polyadenylation specificity factor subunit 5 (CPSF5) is an enzyme that in humans is encoded by the NUDT21 gene. It belongs to the Nudix family of hydrolases.

In the Vinony graph

Within Vinony's link graph, NUDT21 is referenced by 6 other articles, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.

Vinony files it under Genes on human chromosome 16 and Nudix hydrolases.

Its subject is documented across 4 Wikipedia language editions.

Gene data

NUDT21

Name: nudix hydrolase 21
Type: protein-coding
Aliases: CFIM25, CPSF5

The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

nudix hydrolase 21

Symbol: NUDT21
Biotype: Protein coding
Organism: Homo sapiens
Location: 16:56,428,473-56,452,199
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein NUDT21 PDB 2cl3.png

Show 7 more facts

HomoloGene ID: 5090
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/11051
genomic end: 56486111
genomic start: 56463045
chromosome: human chromosome 16
cytogenetic location: 16q13

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

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Contents

References
Further reading

Cleavage and polyadenylation specificity factor subunit 5 (CPSF5) is an enzyme that in humans is encoded by the NUDT21 gene. It belongs to the Nudix family of hydrolases.

The protein encoded by this gene is one subunit of the cleavage factor Im complex required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.

Excerpted from Wikipedia’s “NUDT21” article, available under the CC BY-SA 4.0 licence.