NUDT3
Sign in to saveAlso known as DIPP, DIPP-1, DIPP1, nudix hydrolase 3
Diphosphoinositol polyphosphate phosphohydrolase 1 is an enzyme that in humans is encoded by the NUDT3 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to NUDT3, and connects out to Q180686, human chromosome 6 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 6 and Nudix hydrolases.
Vinony links it to 5 Wikipedia language editions.
Gene data
NUDT3- Name
- nudix hydrolase 3
- Type
- protein-coding
- Position
- 34,263,257–34,392,832 (−)
- Aliases
- DIPP, DIPP-1, DIPP1
- Ensembl
- ENSG00000272325
- RefSeq RNA
- NM_006703.4
- RefSeq protein
- NP_006694.1
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM, Feb 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
nudix hydrolase 3
- Symbol
- NUDT3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:34,263,257-34,392,832
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein NUDT3 PDB 2fvv.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/11165
- HomoloGene ID
- 31400
- genomic end
- 34392669
- genomic start
- 34247456
- cytogenetic location
- 6p21.31
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Diphosphoinositol polyphosphate phosphohydrolase 1 is an enzyme that in humans is encoded by the NUDT3 gene.
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998).[supplied by OMIM]
Excerpted from Wikipedia’s “NUDT3” article, available under the CC BY-SA 4.0 licence.