NUDT6
Sign in to saveAlso known as ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1, nudix hydrolase 6
Nucleoside diphosphate-linked moiety X motif 6 is a protein that in humans is encoded by the NUDT6 gene.
Gene data
NUDT6- Name
- nudix hydrolase 6
- Type
- protein-coding
- Position
- 122,886,565–122,922,968 (−)
- Aliases
- ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1
- Ensembl
- ENSG00000170917
- RefSeq RNA
- NM_007083.5, NM_198041.3
- RefSeq protein
- NP_009014.2, NP_932158.1
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
nudix hydrolase 6
- Symbol
- NUDT6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:122,886,565-122,922,968
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Nucleoside diphosphate-linked moiety X motif 6 is a protein that in humans is encoded by the NUDT6 gene.
FGF2 (MIM 134920) is a highly conserved, multifunctional heparin-binding growth factor involved in neuroectoderm development, angiogenesis, and wound healing.
Excerpted from Wikipedia’s “NUDT6” article, available under the CC BY-SA 4.0 licence.