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O-acetylserine

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EntityQ309897· pop 8· linked from 14 articles

O-acetylserine

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Also known as L-Serine, acetate (ester), O3-acetyl-L-serine, O-acetyl-L-serine

'''O-Acetylserine' is an α-amino acid with the chemical formula HO2CCH(NH2)CH2OC(O)CH3. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. O-Acetylserine is biosynthesized by acetylation of the serine by the enzyme serine transacetylase. The enzyme O''-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releasing acetate: HO2CCH(NH2)CH2OH → HO2CCH(NH2)CH2OC(O)CH3 HO2CCH(NH2)CH2OC(O)CH3 → HO2CCH(NH2)CH2SH

Chemical data

Formula
C5H9NO4
Molecular weight
147.13 g/mol
IUPAC name
(2S)-3-acetyloxy-2-azaniumylpropanoate
SMILES
CC(=O)OC[C@@H](C(=O)[O-])[NH3+]
InChIKey
VZXPDPZARILFQX-BYPYZUCNSA-N
XLogP
-2.8
Polar surface area
94.1 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Wikidata facts

Mass
147.053
Show 5 more facts
chemical formula
C₅H₉NO₄
isomeric SMILES
CC(=O)OC[C@@H](C(=O)O)N
canonical SMILES
CC(=O)OCC(C(=O)O)N
found in taxon
Homo sapiens
subject has role
primary metabolite
Sources (3)

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Encyclopedic overview

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Contents
  • References

'''O-Acetylserine' is an α-amino acid with the chemical formula HO2CCH(NH2)CH2OC(O)CH3. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. O-Acetylserine is biosynthesized by acetylation of the serine by the enzyme serine transacetylase. The enzyme O''-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releasing acetate: HO2CCH(NH2)CH2OH → HO2CCH(NH2)CH2OC(O)CH3 HO2CCH(NH2)CH2OC(O)CH3 → HO2CCH(NH2)CH2SH

==References==

Excerpted from Wikipedia’s “O-acetylserine” article, available under the CC BY-SA 4.0 licence.

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